English

Noun

monotreatment

1. treatment of mononucleosis
   • 2015 September 12, “Phosphoflow-Based Evaluation of Mek Inhibitors as Small-Molecule Therapeutics for B-Cell Precursor Acute Lymphoblastic Leukemia”, in PLOS ONE, DOI:10.1371/journal.pone.0137917:

     Irving et al [5 ] recently applied this principle to test the non-ATP competitive Mek1/2 inhibitor selumetinib (AZD6244, ARRY-142886) as monotreatment for childhood ALL in preclinical studies and concluded that clinical evaluation of selumetinib is warranted.