English

Noun

goitrogen ‎(plural goitrogens)

1. Any agent that causes goiter, such as thiouracil.
   • "We have previously shown that treating rats with the reversible goitrogen 6-propyl-2-thiouracil (PTU) from birth to Day 25 increases testis size and sperm production in adulthood by up to 80% and 140%, respectively."^[3]
   • "These results suggest that excess iodine induces thyroid involution in goitrogen-treated rats at least partially by apoptosis."^[4]

Derived terms

• goitrogenic

References

1. ↑ Goitrogen in Dictionary.com
2. ↑ Goitrogen in Merriam-Webster
3. ↑ P. S. Cooke, J. Porcelli, R. A. Hess. Induction of increased testis growth and sperm production in adult rats by neonatal administration of the goitrogen propylthiouracil (PTU): the critical period. Biology of Reproduction. January 1992;46(1):146-54.
4. ↑ [R. B. Burikhanov and S. Matsuzaki. Excess iodine induces apoptosis in the thyroid of goitrogen-pretreated rats in vivo. Thyroid. February 2000;10(2):123-9.]